Outer membrane vesicles: moving within the intricate labyrinth of assays that can predict risks of reactogenicity in humans
نویسندگان
چکیده
منابع مشابه
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This review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (OMVs), originating from the surface of Gram negative bacteria including their outer membrane proteins and lipopolysaccharides. Moreover, the functional roles and applications of OMVs in medical research such as OMV-based vaccines, OMV adjuvants properties, OMV ...
متن کاملImmunogenicity of enterotoxigenic Escherichia coli outer membrane vesicles encapsulated in chitosan nanoparticles
Objective(s): Enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrheal disease in humans, particularly in children under 5 years and travelers in developing countries. To our knowledge, no vaccine is licensed yet to protect against ETEC infection. Like many Gram-negative pathogens, ETEC can secrete outer membrane vesicles (OMVs). These structures contain various immunogenic vi...
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ژورنال
عنوان ژورنال: Human Vaccines & Immunotherapeutics
سال: 2020
ISSN: 2164-5515,2164-554X
DOI: 10.1080/21645515.2020.1780092